Description
Product Characteristics:
Aliases: 50 DAG antibody, 50 kDa dystrophin associated glycoprotein antibody, 50 kDa dystrophin-associated glycoprotein antibody, 50DAG antibody, 50kD DAG antibody, 59 kDa antibody, A2 antibody, adhalin antibody, ADL antibody, Alpha SG antibody, Alpha-sarcoglycan antibody, Alpha-SG antibody, Asg antibody, DAG2 antibody, DMDA2 antibody, Dystroglycan 2 antibody, Dystroglycan-2 antibody, LGMD2D antibody, sarcoglycan, alpha (dystrophin-associated glycoprotein) antibody, SCARMD1 antibody, Sgca antibody, SGCA_HUMAN antibody
Target Information: This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]